Professor &
Head of
Clinical Microbiology Division,
Department of Laboratory Medicine,
All India Institute of Medical Sciences(AIIMS)
New Delhi-1100029, India
Ph: (+91-11) 2658-8484 / 2659-4977
Fax: (+91-11) 2658-8663/ 2658-8641
Cell No: (0)9810813435
Email:
sarman_singh@yahoo.com ssingh56@hotmail.com
RESEARCH INTEREST
Leishmania
Developing chimeric DNA Vaccine against Leishmaniasis and Tuberculosis.
Screening and selection of novel anti-leishmanial active compounds against leishmania from Indian herbs.
Development of indigenous PCR and serodiagnostic kits for human & animal toxoplasmosis.
Molecular Epidemiology and development of VL and PKDL specific PCR primers.
Tuberculosis
Elucidating the drug resistance mechanism of M. tuberculosis using genomic, proteomic and bioinformatics strategies.
Identification and characterization of novel proteins / antigens for serodiagnosis of multi drug resistance tuberculosis.
Analyzing the genomic architecture of ABC transporters of M. tuberculosis and M. avium subsp. paratuberculosis through bioinformatics methods.
Developing mono and multiplex PCR system for species specific identification of different mycobacterial species.
Lineage analysis of M. tuberculosis and contact investigation in household contacts through various molecular genotypic tools.
Prevalence of Non Tubercular mycobacterial infection of HIV positive and HIV negative patients.
Sequence based Genotyping of mycobacteria isolated from various clinical sites in HIV positive and negative patients.
Virology
Revaluation of NASBA-Nuclisens methods with in-house real time PCR methods and HIV and HSV viral load monitoring.
Prevalence of HBV, HCV and various HHVs in tertiary care hospital setting.
HHVs as co-pathogens in HIV progression and transmission.
The role of TNF-alfa and IFN-gama and the success of Anti-tubercular therapy in Immune Reconstitution Disease in HIV/TB coinfected patients responding to Anti-retroviral therapy.
HBV mutation studies.
Other
Developing a novel multiplex PCR system for simultaneous detection and differentiation of Salmonella, Giardia lamblia, Entamoeba histolytica, Hepatitis A & E directly from drinking water samples.
